THC and CBD are both compounds that are found in cannabis plants, but they have different effects on the body and mind. THC is the main psychoactive ingredient in marijuana, which means it can make you feel high, euphoric, relaxed, or hungry. CBD is not psychoactive, which means it does not cause a high or alter your perception. CBD can have various health benefits, such as reducing pain, inflammation, anxiety, depression, and seizures. Some people use CBD to counteract the negative effects of THC, such as paranoia or anxiety. THC binds with the CB1 receptors in the brain and spinal cord, while CBD interacts with receptors in muscle tissue including the heart. CBD is legal nationally in the U.S., whereas THC remains federally criminalized and is only legally available on a state-by-state basis.